Friday, December 10, 2004

Thirty six years old man with HIV

Case by Luis Tata, MD


Fig. 1 Unenhanced CT Posted by Hello

3 comments:

Sumer Sethi said...

i think the diagnosis is pneumocystis carnii!!!

http://www.sumerdoc.blogspot.com

lmt said...

Right. But can you be more precise?

lmt said...

Pneumocystis carinni pneumonia, cystic form.

View case

Pneumocystis carinni pneumonia (PCP) is the commonest causative agent of pneumonia in HIV-infected patients (60-75% of all patients have at least one episode of PCP).
The infection rate as been declining since the introduction of inhalational chemoprophylaxis.
The inicial appearance of PCP is that of a predominantly alveolar process with patchy grouns glass opacities showing a diffuse bilateral distribution with perihilar accentuation.
In patients receiving prophylatic aerosol therapy, the changes show an upper zone predominance.
With further progression of the infection, immunocompromised patients develop extensive consolidation with an air bronchogram while immunocompetent patients (receiving treatment) show a granulomatous reaction with interstitial fibrosis and nodular changes.
AIDS patient receiving prophylatic treatment with aerosolized pentamidine are the subgroup most likely to develop destructive cystic lung changes (pneumatoceles or thick-walled cysts), which predominantly involve the upper lobes and the apical segments of the lower lobes.
Prokop, Mathias. Spiral and Multislice Computed Tomography of the Body. 2003 Georg Thieme Verlag